The Precision PCI registry aims to enhance precision medicine in antiplatelet therapy post-PCI by focusing on CYP2C19 genotype-guided strategies. It seeks to address gaps in current knowledge, particularly in African ancestry patients, and evaluate the safety and effectiveness of therapy de-escalation. The study involves a diverse cohort of over 6000 patients and aims to inform better drug selection to improve clinical outcomes. The registry will also explore genetic associations with clopidogrel response, providing insights into patient-specific factors influencing therapy effectiveness.

The Department of Justice (DOJ) announced a new Mergers & Acquisitions (M&A) Safe Harbor Policy aimed at encouraging compliance by providing protections for acquiring companies that disclose criminal conduct discovered during the M&A process. Deputy Attorney General Lisa Monaco emphasized the DOJ's commitment to transparency and predictability in corporate criminal enforcement, particularly in areas intersecting with national security. The policy requires companies to disclose misconduct within six months of closing and remediate within a year to qualify for safe harbor. The policy applies department-wide and aims to standardize DOJ's approach to corporate crime, though its implementation may vary across different DOJ components. The policy does not apply to the acquired entity but incentivizes acquiring companies to conduct thorough due diligence and compliance integration.

The Supreme Court has agreed to hear two consolidated False Claims Act (FCA) cases to determine if a defendant's subjective understanding of the lawfulness of their conduct is relevant to whether they 'knowingly' violated the FCA. The cases involve allegations that SuperValu Inc. and Safeway, Inc. overcharged Medicare and Medicaid for generic drugs by not including all available discounts in their pricing. The Seventh Circuit previously ruled in favor of the defendants, applying the 'Safeco standard' which allows for an objectively reasonable interpretation of ambiguous regulations. The Supreme Court's decision could significantly impact the scope of FCA liability and the burden on companies receiving government funds.

Wolves are nearing a £20.5m deal to sign Burnley centre-back Nathan Collins, which would be the highest fee ever paid for an Irish player. Collins, who joined Burnley last summer for £12m from Stoke, has earned six caps for the Republic of Ireland. The 21-year-old, who can also play as a right-back, is expected to be Wolves' first summer signing under manager Bruno Lage. Despite Burnley's relegation, Collins had a commendable season with 19 Premier League appearances and two goals. Wolves aim to strengthen their squad ahead of the new season, starting with a match against Leeds on August 6.

Students at the University of Massachusetts Amherst are outraged after Black organizations received a racist email. Vice-Chancellor Nefititi Walker condemned the email and announced a multi-unit investigation. The email, signed by 'The UMass Coalition for a better society,' contained vile and offensive content. University officials are seeking student cooperation for further information, while Black students demand more proactive safety measures from the school.

The study explores the self-empowerment process of street food vendors, a marginalised community within the hospitality industry. It critiques top-down empowerment programs and emphasizes the importance of understanding the internal empowerment process of individuals. Using a critical paradigm and qualitative research design, the study conducted 25 online unstructured interviews with street food vendors in Indonesia. Thematic analysis revealed three key themes: consciousness, autonomy, and agency. The study also highlights the necessity of tailored external support, acknowledging the unique barriers faced by each individual.

Montana of 300, a Southside Chicago-born rapper, is concluding his solo music career with his final album 'Rap God'. He plans to focus on promoting artists under his Fly Guy Entertainment label and exploring new ventures such as writing books and movie scripts. Montana reflects on his career, emphasizing his independent path and the importance of planning an ending. He also discusses his future projects, including joint music projects with his label's artists and involvement in youth sports through FGE Sports.

The Federal Trade Commission (FTC) has taken unprecedented steps against noncompete agreements, suing three companies and proposing a rule to ban nearly all employee noncompetes in the U.S. The FTC's actions target Prudential Security, O-I Glass Inc., and Ardagh Group S.A., alleging these companies imposed unlawful noncompetes on employees. The proposed rule, if finalized, would invalidate existing noncompetes and face significant legal challenges. The FTC's moves align with President Biden's executive order on competition and signal a broad application of the Section 5 Policy Statement. Commissioner Christine Wilson dissented, arguing the actions lack evidence of anticompetitive effects and could set a harmful precedent.

Carl Cavalier, a Black Louisiana state trooper, accuses the Louisiana State Police Department of retaliating against him for criticizing their handling of Ronald Greene's death during a 2019 traffic stop. Cavalier, who has been on paid leave since August, received a letter warning of his potential termination for various violations. He vows to fight for his job, citing his oath to uphold justice. The incident involving Greene, who died after being beaten by troopers, has sparked controversy and calls for transparency. The NAACP supports Cavalier's stance, emphasizing the need for accountability within the police force.

Kim Kardashian hosted Saturday Night Live on October 9, delivering a monologue that humorously targeted her family, friends, and herself. She wore pink and made jokes about OJ Simpson, her estranged husband Kanye West, and Caitlyn Jenner, among others. Kanye West was reported to be in New York to support her SNL debut.