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Check FAQAbout David
David Chisanga is a Zambian media and communications specialist based in Limerick, Ireland. He is an award-winning journalist; a journalist mentor; a TV and radio broadcaster; a blogger; a scriptwriter; and a public relations (PR) personnel. His career spans over five (5) years with experience in broadcast journalism, print and online journalism, radio and TV production, filmmaking, academia and PR. Recently, he was a news/documentary producer at the Ministry of Agriculture in Zambia. He was also a news editor at Lima Radio. He is currently a freelance journalist and filmmaker in Ireland. Although David can cover any beat assigned to him very well, his interest lies in business and economics. He is one of the graduates from the 2019 Bloomberg Media Initiative Africa (BMIA) Financial Journalism Training Programme. He holds a Master of Arts (MA) in Media Studies from Mary Immaculate College (MIC) and a Bachelors in Mass Communication from the University of Zambia (UNZA). He is an alumni of Radio Netherlands Training Centre (RNTC), where he studied Drama for Social Change. David has worked with Africa News at international level. He is ready to spread his wings in international journalism and fly.
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Portfolio
A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development
A feedforward circuit between tuft cells and type 2 innate lymphoid cells (ILC2s) promotes gastric metaplasia and cancer. Inhibiting this interaction with specific antibodies can reduce tumor growth, presenting a potential therapeutic target for gastric cancer treatment. Gastric cancer, a leading cause of cancer-related mortality, is often preceded by chronic gastric metaplasia, which is linked to persistent bacterial infections. Tuft cells, identified by specific markers, and ILC2s, which respond to cytokines like IL25 and IL13, play crucial roles in this process. The study demonstrates that disrupting the tuft cell-ILC2 circuit can inhibit tumor development in mouse models, suggesting similar therapeutic strategies could be effective in humans. The findings highlight the potential of targeting cytokine signaling pathways to treat gastric cancer.
The Food Reserve Agency (FRA) has continued buying Grade A white maize from farmers countrywide to enhance Zambia’s food security.
David Chisanga news casting.
David Chisanga news casting
Government has launched the 2021 Foot and Mouth Disease – FMD – mass vaccination exercise aimed at reducing transmission of the disease in Zambia. Here's DAVID CHISANGA with more details.
Zambia is envisioned to become a net exporter of fish in Africa in the next five years. DAVID CHISANGA has more.
Zambia has observed its first ever International Day of Plant Health in the capital, Lusaka. This comes after the UN General Assembly adopted the country’s proposal to observe this important day on 12 May every year. DAVID CHISANGA has the details.
David M.S. Chisanga
The article discusses the impact of climate change on agriculture in Zambia, highlighting the challenges faced by farmers like Mweene Habenzu and Simon Simukwanya due to unpredictable weather patterns, poor yields, and new pests. It emphasizes the importance of climate smart agriculture as a solution, which involves planting climate-resistant seeds and adopting practices like crop diversification, agroforestry, and conservation farming. The article mentions the efforts of Pannar Seed Zambia in developing climate smart seeds and the Zambia Agricultural Research Institute (ZARI) in enhancing climate smart agriculture through research and development of drought-resistant crop varieties and promoting sustainable farming practices.
This documentary, which I scripted and edited, highlights E-SAPP interventions in the Soya Beans Value Chain in Zambia.
The World Bank has praised Zambia for promoting irrigation farming through infrastructure development. DAVID CHISANGA reports.
Early precursor T cells establish and propagate T cell exhaustion in chronic infection
High antigenic load during chronic infection facilitates the early differentiation of virus-specific TCF1+ID3+ precursor T cells (TP cells), which acquire features of exhaustion early on. These TP cells exhibit reduced effector function but maintain high proliferative and developmental potential, contrasting with effector T cells (TE cells) that show reduced proliferative potential. The study identifies BACH2 and BATF as critical regulators of TP cell generation, with BACH2 promoting and BATF inhibiting TP cell differentiation. The findings suggest that T cell exhaustion is an active process that protects TP cells from full differentiation, preserving their function during prolonged infections.
Author Correction: Sex-specific adipose tissue imprinting of regulatory T cells
Corrections have been made to the original article regarding the y-axis label in Fig. 1a, a number in the flow cytometry plot in Fig. 4j, and the strain associations in the Methods subsection 'Mice'. The original article has been updated online to reflect these changes.
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