ERAMER is a newly developed in silico tool designed to predict the trimming specificity of the ERAP1 enzyme, which plays a crucial role in the MHC class I pathway by processing peptides for immune surveillance. The tool utilizes a mathematical model to predict the likelihood of peptides being preferred by ERAP1, aiding in the understanding of peptide presentation on cell surfaces. The study highlights the importance of ERAP1 in generating optimal peptides and its potential impact on T-cell responses.

Tech Takes a Break is an initiative that highlights the personal hobbies and interests of tech professionals, aiming to foster a more inclusive community. The first episode features Andrea Cervone, a tech influencer from Bari, Italy, who combines his passion for technology with motorbiking adventures. The initiative seeks to promote a healthier work-life balance by showcasing diverse hobbies and encouraging tech enthusiasts to explore new skills through events and workshops.

Elisabetta Bruno, CEO and founder of Thinkable, shares insights into her daily life, career challenges, and aspirations. She emphasizes the importance of maintaining a balance between personal and professional life while leading a dynamic company. Thinkable focuses on CRM marketing and aims to provide operational strategies for businesses. Bruno is also involved in developing an app for marketing activities and a training course. She highlights the significance of small, specialized companies in the technology sector and expresses a desire to increase Thinkable's market visibility. Bruno values personal development and collaboration, drawing inspiration from influential figures like Robert Downey Jr. and Leonardo Di Caprio.

Artificial Intelligence is revolutionizing the search for extraterrestrial intelligence, with the SETI Institute at the forefront. Collaborating with the National Radio Astronomy Observatory, SETI is developing AI-driven software to process vast amounts of data from the Very Large Array in New Mexico. This initiative aims to enhance the detection of alien signals by identifying irregularities in the data. Despite decades of searching, the quest for extraterrestrial life remains challenging, but AI offers new hope in this scientific endeavor.

Ukrainian troops attacked bridges between Kherson and Crimea, causing significant damage to the Chongarsky bridge. Kherson's governor, Volodymyr Shaldo, condemned the attack and promised repairs. Despite the damage, communication between the regions continues via alternative routes. British-made Storm Shadow missiles were reportedly used. Crimean leader Sergei Aksyonov and other officials are assessing the damage and investigating the type of ammunition used. The attack has not significantly impacted logistical support to Crimea.

The Russian Ministry of Defense released a video showcasing the combat operations of the 2A36 Giatsint-B artillery in the Ukrainian war zone. Russian forces, including snipers and artillery units, have been targeting fortified Ukrainian positions and transport hubs. A Russian Su-34 bomber recently struck a gathering of foreign mercenaries in the Kharkiv region. The Russian military has also thwarted several Ukrainian attempts to advance. The Su-34, along with other aircraft like the Su-25, continues to play a significant role in the conflict, often engaging in missions to support ground operations and counter Ukrainian air defenses.

Meta's ambitious Metaverse project faces significant challenges, with internal and external skepticism growing. Despite substantial investments and advertising efforts, the focus appears to be shifting towards augmented reality rather than virtual reality. Key figures like Andrew Bosworth and John Carmack highlight the company's strategic pivot, while user engagement in platforms like Horizon Worlds declines. The future of the Metaverse remains uncertain, with potential failure looming over Meta's broader technological aspirations.

The article discusses the challenges faced by start-ups in raising investment capital, highlighting the success of Protex AI, which raised $18 million. Founders Dan Hobbs and Ciarán O’Mara shared their experiences at the Dublin Tech Summit, emphasizing the importance of persistence, networking, and understanding investor interests. Protex AI, working with brands like Marks & Spencer, uses AI and computer vision technologies to improve workplace safety. The company secured funding from notable investors including Notion, Playfair, Firstminute, Elkstone, and Y Combinator. The article also touches on the low success rate of start-ups in securing funding and the importance of building trust with investors over time.

Dyson has developed a portable air quality backpack that allows users to monitor air pollution in real-time. This device, which uses technology from Dyson air purifiers, can measure various pollutants and is accompanied by the Dyson Air Quality app for data analysis and visualization. The company is promoting awareness about air pollution through an online campaign and collaborations with influencers. The backpack was tested in Delhi NCR, where it tracked a mother's exposure to pollutants during her daily activities. Dyson has also introduced the Dyson Zone, a portable air purifier and noise-cancelling headphones combo. The company emphasizes its commitment to innovation and plans to expand its team of software developers to continue advancing its smart appliance technology.

Former US President Barack Obama discussed the challenges and dangers of Artificial Intelligence (AI) at the SNF Nostos Conference in Athens, organized by the Stavros Niarchos Foundation. He highlighted the potential for AI to disrupt jobs, especially routine ones, and the intensifying problem of misinformation, exacerbated by social media. Obama emphasized the need for governments and businesses to be equipped to harness AI's benefits while mitigating its risks, including the call for regulation. He also touched upon the broader challenges of the digital age, such as the impact on democracy and the need to educate youth to discern truth from falsehood. The discussion is part of the broader work of the Obama Presidential Center's Democracy In Action Lab.