Hospitals have undergone significant transformations in financing and management to meet increasing healthcare demands. The implementation of evidence-based practices, such as the clinical guidelines of the Registered Nurses' Association of Ontario (RNAO) and the Best Practice Spotlight Organizations (BPSO®) program, is essential for improving care quality. Collaboration between RNAO and the Ministry of Health (MINSAL) in Chile underscores the importance of innovation and excellence in healthcare. Despite substantial improvements, the implementation of RNAO's guidelines faces political, organizational, and professional barriers. Addressing these challenges through implementation science is crucial for enhancing evidence-based care and ensuring active participation from nursing professionals in continuous quality improvement.

Street vendors earn significantly more than small and medium-sized enterprises (SMEs) due to not paying various taxes and fees, creating unfair competition. Government policies, including recent tax reforms, are seen as detrimental to SMEs, which are crucial for employment and social mobility in Chile. The article argues for reducing bureaucratic and tax burdens on SMEs to combat informality and promote entrepreneurship, criticizing current government actions as counterproductive.

Triple negative breast cancer is marked by a high relapse rate and poor prognosis, with survival not exceeding 2 years from the onset of distant metastases. This is largely due to high intratumoral heterogeneity, lack of identifiable druggable oncogenic targets, and greater tumor aggressiveness, leading to high therapeutic resistance rates. The article explores new therapeutic strategies under study, including drug-conjugated antibodies, antiandrogenic endocrine therapy, PARP inhibitors, immune checkpoint inhibitors, and/or cell therapy, either as monotherapy or in various combinations, aiming to impact the survival of patients with advanced triple negative breast cancer.

Two bronze incense burners, preserved in a fragmentary state at the Albacete Museum for over a decade, are believed to originate from the province. The first is identified as a 'Cypriot' stand of Western manufacture, while the second is a flared-foot burner with feline claws, typical of Western Phoenician craftsmanship. These artifacts enhance the understanding of archaic bronze work in the southeastern Meseta and contribute to the list of such cult objects in the Iberian Peninsula.

Increasing the number of nursing professionals in Chilean hospitals is crucial for improving patient outcomes and reducing mortality rates. Current staffing levels are below international standards, with public hospital nurses attending to an average of 14.1 patients each. Studies show that higher patient-to-nurse ratios significantly increase the risk of patient death and readmission. Chile graduates nearly six thousand new nurses annually, enough to meet the required staffing levels. Policymakers must collaborate to create sustainable jobs and improve public healthcare quality.

Manchester United is considering a significant overhaul of its squad following a disappointing season and a recent defeat to Sevilla FC. Up to 17 players, including key figures like David De Gea and Harry Maguire, may be on their way out as the club aims to rebuild under manager Erik ten Hag. The potential exits also include players like Fred, McTominay, Anthony Elanga, and Anthony Martial, among others. Loaned players Weghorst and Sabitzer are set to return to their parent clubs, Bayern de Múnich and Burnley, respectively.

FC Barcelona is looking to make budgetary room for new signings, including the potential return of Lionel Messi. To facilitate financial maneuvers, the club is considering selling players, including Clement Lenglet, who could leave for a price much lower than his original signing cost. Lenglet, who has not been a key player for Barcelona for a couple of seasons and is currently on loan at Tottenham, is not in the club's plans, especially with players like Koundé, Christensen, and the potential signing of Íñigo Martínez. Tottenham is interested in signing Lenglet, and Barcelona has set a price for the transfer.

Xabi Alonso's impressive performance as the coach of Bayer Leverkusen has caught the attention of Real Madrid. The former Real Madrid player has led the German team from relegation positions to European competition spots and into the Europa League semifinals. Real Madrid is considering Alonso as a potential future coach to replace Carlo Ancelotti, with a possible move at the end of the season.

Real Madrid is planning several moves in the summer transfer market, prioritizing the signing of Jude Bellingham from Borussia Dortmund. The club also aims to strengthen its defense and attack, considering alternatives for the right and left-back positions due to Dani Carvajal's underperformance and the unsuccessful transfer of Eden Hazard.

Napoli is one of the most prolific teams in Europe, leading Serie A by fourteen points over Lazio. Despite their elimination from the Champions League by Milan, Napoli is focused on securing the 'Scudetto' and is planning for the next season. They are particularly interested in Argentine rising star Thiago Almada, for whom they might make a substantial offer.

Chelsea recently dismissed Graham Potter after a disappointing season and is now seeking a new coach. Frank Lampard's arrival has not been effective, and the club is considering Julian Nagelsmann as the favorite, while also initiating contact with Mauricio Pochettino. Luis Enrique was another option but has been nearly ruled out. The club aims to make a well-considered decision, as reported by Fabrizio Romano.

FC Barcelona, facing financial constraints, is prioritizing certain summer market moves, with optimism surrounding Lionel Messi's return and Ilkay Gündogan as another priority. The club has pending renewals for players like Gavi and Ousmane Dembélé. Consequently, Barcelona is setting aside the potential signing of Carrasco, which would only be considered as a last resort.

Hugo Mallo, a long-time player for Real Club Celta de Vigo, will leave the club at the end of the season as he has decided not to renew his contract. At 32, Mallo aims to play in a foreign league, with the MLS being a likely destination. Although Atlético Mineiro showed interest, no agreement was reached. Mallo is now set on joining a team in either the United States or Canada.

Chelsea has ruled out Luis Enrique as a candidate for their next coach and is now deciding between Julian Nagelsmann and Mauricio Pochettino. While Nagelsmann is the primary candidate, Pochettino remains a strong contender. Meanwhile, Luis Enrique is reportedly being considered by Tottenham Hotspur.

Joaquín Sánchez, a veteran footballer known for his significant contributions to Real Betis Balompié, has announced his retirement at the age of 41. Having played for various teams including Valencia, Málaga, and Fiorentina, Joaquín is most celebrated for his time with Betis. His retirement marks the end of an era, leaving Betis stronger and more consolidated than when he rejoined the team in his second stint.

Real Madrid has reportedly renewed Karim Benzema's contract until June 2024, coinciding with the expected arrival of Brazilian player Endrick. Despite Benzema's renewal, the club faces challenges in its forward line and may need to sign a reliable striker to ensure Endrick's smooth adaptation. Haaland is mentioned as a dream addition, though other options are also considered. The renewal is linked to the 'Ballon d'Or clause,' and while formalities are not yet complete, the information is deemed credible.

AC Milan is working on renewing contracts for key players, including Rafael Leao and Mike Maignan, to maintain their strong squad. Olivier Giroud has already renewed his contract. Arsenal and Tottenham Hotspur are interested in signing Maignan, whose impressive performance this season has caught their attention.

Olympique de Marseille has decided not to exercise the purchase option for Eric Bailly, who will return to Manchester United. However, Manchester United does not plan to keep him for the next season and will put him up for sale. Sevilla FC is considering selling Karim Rekik, who has struggled with injuries, and sees Bailly as a viable and economical replacement to strengthen their defense.

AC Milan has decided to renew the contract of veteran French forward Olivier Giroud, extending his stay with the club until June 2024. The decision follows weeks of negotiations, with both parties eager to reach an agreement, ultimately leading to Milan taking the initiative to finalize the deal.

Atlético de Madrid is looking to sell Joao Félix, but his inconsistent performance has made it difficult. Chelsea has ruled out paying the high transfer fee, but there is rumored interest from the Premier League, particularly from Newcastle United, which might be willing to meet the asking price.

Paris Saint-Germain is planning a significant move in the summer transfer market to convince French star Mbappé, whose contract ends in 2024, to potentially extend his stay until 2025. The club's strategy includes hiring José Mourinho, a multiple Champions League winner, as the new coach, and signing Harry Kane to bolster their attack, with the aim of competing for the Champions League next season. Current coach Galtier is expected to leave at the end of the season, and Messi's future is also uncertain.

Sevilla FC has experienced a remarkable turnaround under the guidance of José Luis Mendilíbar after a disastrous season with multiple coaching changes. Mendilíbar's success is attributed to a shift towards more direct football, reducing completed passes and increasing aerial duels, leading to second-chance goals. New players like Gueye, Bryan Gil, and Loïc Badé, along with the leadership of Marcao in defense, have significantly improved the team's performance.

Real Madrid is prioritizing the signing of Jude Bellingham, competing mainly with Manchester City and negotiating with Borussia Dortmund, which demands a high price. Liverpool has withdrawn from the race. Real Madrid is considering including Brahim Díaz in the deal to facilitate the transfer, with initial contacts reportedly underway.

Borussia Monchengladbach is set to face significant player departures, with Ramy Bensebaini available as a free agent and Marcus Thuram becoming a highly coveted attacker. Bensebaini, previously a target for Atlético de Madrid, has chosen to join Borussia Dortmund, with a personal agreement already in place as confirmed by Fabrizio Romano, and an official announcement is expected soon.

Liverpool has been seeking a reliable midfielder since Wijnaldum's departure, with Jürgen Klopp exploring various options. After ruling out Bellingham, Liverpool considered Ryan Gravenberch due to his limited playtime at Bayern Munich. However, Bayern Munich, under Thomas Tuchel's future plans, has decided to keep Gravenberch, forcing Liverpool to refocus on Mason Mount, who might leave Chelsea this summer.

Graham Potter, formerly of Chelsea, is seeking a new managerial role after being replaced by Frank Lampard due to the team's mediocre performance in the Premier League and challenging position in the Champions League. West Ham United, facing relegation, is considering Potter as a replacement for David Moyes for the next season, as reported by Daily Mail.

Luis Enrique, the former Spain national team coach, is looking to return to club management, with the Premier League showing the most interest. While Chelsea has been linked with him, they are currently focused on Julian Nagelsmann. According to The Telegraph, Tottenham Hotspur is now the primary club interested in Luis Enrique, aiming to have him lead their new project to return to European competition. Other candidates for the Tottenham job include Vincent Kompany and Mauricio Pochettino, with the latter being Enrique's main rival.

Chelsea FC is on the verge of signing Kendry Páez, a 15-year-old Ecuadorian footballer from Independiente del Valle, for around 20 million euros. The offensive midfielder, noted for his talent, will join Chelsea at Stamford Bridge in 2025 when he turns 18. The Premier League is close to approving the deal, which has been confirmed by Fabrizio Romano.

Falorin Balogun, currently excelling on loan at Stade de Reims with 19 goals, faces tough competition for a spot in Arsenal's attack led by Gabriel Jesús and Nketiah. As a result, Balogun is attracting interest from Red Bull Leipzig and AC Milan, with his future at Arsenal uncertain unless he can secure a prominent role.

Newcastle United has made significant strides in their squad, aiming for Champions League positions next season. Currently fourth in the Premier League, they are motivated to climb higher. Initially not planning to spend much in the summer market, their realistic Champions League prospects have led the management to align with coach Eddie Howe's ambitious plans. The club's main targets for strengthening the squad are Maddison, Ivan Toney, and Declan Rice, with potential spending exceeding 200 million.

FC Barcelona is under scrutiny due to the unresolved Negreira case, but President Joan Laporta remains optimistic about winning La Liga and securing new players like Gündogan and Íñigo Martínez. The club is also focused on retaining key players, including working on the renewal of Ousmane Dembélé, who is highly valued by coach Xavi Hernández despite his recent injury.

Chelsea FC has extended Argentine midfielder Enzo Fernández's contract until 2032, demonstrating their commitment to the World Cup champion's future with the club. Despite significant investments in players like Mudryk for 70 million euros and Enzo Fernández for over 100 million euros, Chelsea has struggled to shine in both the Premier League and Europe, failing to overcome Real Madrid. Joao Félix has been a disappointment for the team.

Real Madrid is strongly linked with the signing of Jude Bellingham, despite competition from Manchester City, which has increased pressure on the deal. Bellingham reportedly prefers Real Madrid over Manchester City, which he described as 'a team without soul.' Liverpool has dropped out of the race, while Manchester City is willing to meet Borussia Dortmund's asking price of 130 million euros, compared to Real Madrid's offer of 100 million euros.

Chelsea FC is actively pursuing the signing of Gavi, a key player for FC Barcelona, whose current contract as a reserve team player prevents him from signing a new deal with Barcelona until they resolve their financial issues. Despite an expected promotion to the first team, Barcelona's problems persist, and Gavi could become a free agent on June 30. Chelsea has offered Gavi a significant proposal and has initiated contact with his agent, Iván de la Peña, and his parents to discuss the transfer. Barcelona coach Xavi Hernández considers Gavi's retention crucial, but Chelsea's interest poses a threat to his stay at Camp Nou.

Udinese is set to finalize the signing of Brenner Souza da Silva from FC Cincinnati for approximately 10 million euros. The 23-year-old Brazilian forward, previously linked with Nottingham Forest, will move to Europe to strengthen Udinese's attack. The deal has been confirmed by Italian journalist Fabrizio Romano, with personal terms already agreed upon.

Sevilla FC is facing a challenging season, which has impacted the team's morale. They are struggling to avoid relegation battles in the final games of the season. This situation may lead to complications in the upcoming summer transfer market, which former Sevilla and current Wolverhampton coach Lopetegui aims to capitalize on. He has targeted Marcos Acuña, a key player for Sevilla, to strengthen the British club in the summer.

Alexis Mac Allister, the world champion with Argentina and Brighton player, has been followed by several teams for months. His performance in the Premier League and the World Cup has attracted the attention of major clubs. Atlético de Madrid from La Liga showed great interest, which has waned over time. Fabrizio Romano has confirmed that Brighton will let Mac Allister leave this summer after an agreement between both parties. Mac Allister's market value is 42 million euros, but Brighton will demand a specific amount in the coming weeks from interested parties.

Paris Saint-Germain faces a busy summer market after Messi rejected renewal offers. Luis Campos, tasked with renewing Messi, has failed, leading to significant criticism from the PSG board. The team's poor performance and failure to advance in the Champions League have further eroded confidence in Campos, with signings like Carlos Soler, Fabián Ruiz, and Renato Sanches under scrutiny. Campos is now on the verge of dismissal due to unmet ambitions and disappointing results.

FC Barcelona has proposed a lower renewal offer to Sergio Busquets, aiming to extend his contract for another year at a reduced salary of 7 million euros per season. Despite the significant pay cut, Busquets is considering the offer due to his love for the club, the potential return of Lionel Messi, and the insistence of coach Xavi Hernández. The decision is still pending.

Udinese has officially announced their first signing for the upcoming season, securing Jordan Zemura to strengthen their left-back position. Zemura joins from Bournemouth, currently near relegation in the Premier League, as a free agent after not renewing his contract. The Zimbabwean defender has signed with Udinese until 2027.

Real Madrid, once a leading contender for Jude Bellingham's transfer, faces stiff competition from Manchester United and Manchester City. While Liverpool has shifted focus, Manchester City emerges as a strong favorite, willing to pay up to 120 million euros. Borussia Dortmund is reluctant to let Bellingham go, complicating Real Madrid's efforts despite the player's interest in joining them.

Newcastle United is actively participating in the transfer market to build a competitive team, currently aiming for a Champions League spot. They are targeting Declan Rice, a highly sought-after midfielder, who is also being pursued by Manchester United and Arsenal. Despite Newcastle's recent success, they face stiff competition from more established clubs.

Chelsea has faced a significant economic deficit, spending over 600 million euros on player transfers since last summer, yet achieving poor results in the Premier League. The club, led by Todd Boehly, is criticized for its extravagant spending on players like Mudryk, who have not made a significant impact. Their only hope for salvaging the season lies in their performance in the Champions League against Real Madrid.

Juventus Turin is considering selling Dusan Vlahovic, who has not been performing well, to reinvest in the transfer market. With the team currently in the middle of the Serie A table, a revamp is needed for the next season. Juventus, led by Massimiliano Allegri, has set their sights on Italian talent Matteo Prati as a potential new addition to their squad.

FC Barcelona needs to make sacrifices in the summer to facilitate new signings, including a well-advanced plan to re-sign Leo Messi. Due to significant financial constraints, the club is considering letting go of key players, with Ferrán Torres, Raphinha, and Ansu Fati being the primary candidates. Ansu Fati is the most likely to be sold to generate substantial financial benefit.

Sevilla FC is facing economic issues and is planning a reset after a challenging season, with the risk of relegation still present. The club's director of football, Monchi, is reportedly focusing on three key player sales. The first mentioned is goalkeeper Yassine Bounou, also known as Bono, who has been benched in favor of Dmitrovic by the new coach, Mendilíbar. Bounou is reportedly unhappy with his situation and is looking to leave in the summer, providing Sevilla with an opportunity to profit from his transfer.

Julian Brandt has renewed his contract with Borussia Dortmund until June 2026 after weeks of negotiation, despite being linked with several Premier League clubs. He has chosen to stay at Dortmund, where he feels comfortable. Meanwhile, there are no updates on Jude Bellingham's situation, although the German club is reportedly asking for a significant fee.

Football clubs are increasingly focusing on signing young, promising players, with the Premier League's Wolverhampton recently linked to Ez Abde, who is having an impressive season on loan at Osasuna. Julen Lopetegui sees Abde as a perfect fit for his plans, and Atlético de Madrid is also closely monitoring the Moroccan winger. Despite Abde's desire to return to Barça, the club might sell him for financial reasons.

Arsenal FC's Folarin Balogun, currently on loan at Stade de Reims, is attracting interest from five clubs due to his impressive performance. The 21-year-old striker wishes to return to Arsenal as an important player but is unwilling to go on loan again, which complicates his situation given the form of teammates Gabriel Jesus and Nketiah under coach Arteta.

Messi's return to FC Barcelona is becoming a real possibility, with two out of three conditions already met. Messi has rejected a renewal from Paris Saint-Germain, where he and his family have not felt comfortable, partly due to negative reactions from fans. Barcelona is now working to finalize the deal without interference from PSG's Al-Khelaifi, while Messi is ignoring other lucrative offers, such as one from Al-Hilal in Saudi Arabia.

Football has become a significant entertainment industry, leading to substantial financial growth within the sport. This includes multimillion-dollar contracts for both players and coaches. The article highlights the top three highest-paid football coaches: Cholo Simeone, who earns 40 million euros annually at Atlético de Madrid, and Pep Guardiola, who earns 23 million euros per season at Manchester City.

Romelu Lukaku's return to Inter Milan from Chelsea has not met expectations, with his performance falling short. Recently, Lukaku faced a racism incident during a match against Juventus. His current form has kept him away from the interest of major clubs, raising questions about his future, including whether he will have a place under Frank Lampard.

Manchester City initially signed young talent Romeo Lavia in 2020, but he moved to Southampton after two seasons. Southampton paid 12 million euros for the 19-year-old midfielder, who has since excelled in the Premier League. Pep Guardiola has expressed admiration for Lavia and hinted at the possibility of Manchester City exercising a 40 million euro buy-back option to re-sign him.

Kolo Muani, having an outstanding season with Eintracht Frankfurt, scoring 19 goals and providing 14 assists, is highly sought after in the European football transfer market. Valued at 65 million, his future is now reportedly dependent on the decision of coach Tuchel. Top clubs like Manchester United, Paris Saint-Germain, Bayern Munich, and possibly Real Madrid, with Benzema still in form, are showing interest.

Lionel Messi's future remains uncertain with FC Barcelona emerging as a clear favorite despite their dire economic situation. Barcelona is advancing its projects, such as the new Camp Nou idea, and President Laporta has devised a strategy that could enable Messi's return. However, Messi has more economically favorable options, including staying with Paris Saint-Germain, where he can maintain his elite status and salary. Yet, the relationship between Messi and PSG is deteriorating, and the French fans are not supportive. Other possibilities include moves to the United States or Saudi Arabia.

Arsenal is having a great season, leading the Premier League largely due to a talented young squad under Mikel Arteta. The club is keen on renewing contracts for key players, including Reiss Nelson, who has shown potential despite limited playtime. Arteta believes Nelson, who has scored 3 goals and provided 3 assists in 500 minutes, could become important in the future. Several clubs are interested in Nelson.

FC Barcelona, after a significant defeat against Real Madrid in the Copa del Rey, is focusing on LaLiga and addressing squad issues. The club prioritizes signing a right-back, with Jeremie Frimpong from Bayer Leverkusen emerging as the ideal candidate. Frimpong's impressive season, marked by 8 goals and 9 assists, makes him a valuable target for Barça, which values offensive capabilities in the right-back position.

Liverpool FC is seeking to reinforce their midfield and has been linked with players such as Mason Mount from Chelsea and Moisés Caicedo from Brighton & Hove Albion. The club had previously shown interest in Jude Bellingham but withdrew due to the high transfer fee demanded by Borussia Dortmund. Jurgen Klopp's team is looking to bolster a position where Curtis Jones has not yet secured full confidence.

Frank Lampard is set to return as Chelsea's head coach, which could significantly alter Mason Mount's current situation at the club. Mount, having lost prominence under Graham Potter, has expressed dissatisfaction and appeared to be on his way out, with Liverpool showing interest. However, Lampard's high regard for Mount might restore the midfielder's confidence and prevent his departure from Stamford Bridge.

Chelsea FC has reappointed Frank Lampard as the head coach, leading to potential changes in the team's goalkeeper lineup. Graham Potter's recent dismissal has opened up the competition between Kepa Arrizabalaga and Edouard Mendy for the starting position. The decision on who will be the first-choice goalkeeper rests with Lampard, with reports suggesting that one of the goalkeepers may leave Stamford Bridge.

A set of bronze pieces related to horse governance, including circular beds, a bit, a rein guide, and conical buttons, were found in the necropolises of El Molar and El Llano de la Consolación, and in the collections of the Archaeological Museum of Murcia. The study evaluates the presence and social use of horses at the mouth of the Segura River during the Late Orientalizing and Ancient Iberian periods. These objects, appearing during a cultural transition, indicate the adoption of foreign elements to assert social status amidst instability and change in the region during the second half of the 6th century BC.

This episode of Radio Free Acton features interviews with two individuals discussing different topics. Noah Gould, an intern at Acton, interviews Venezuelan dissident Javier Avila, who shares his perspective on the resistance against the government in Venezuela, painting a picture that is both grim and hopeful. Another intern, Jenna Suchyta, speaks with Jared Meyer from the Foundation for Government Accountability about the sharing economy. The podcast also encourages listeners to engage with additional resources, including articles, a book, and an invitation to the Acton Institute's annual dinner. The episode concludes with a call for listener questions and a prompt to rate the podcast on iTunes.