The study investigates blood plasma markers in mice subjected to chronic social defeat stress, a model for depression. It identifies specific proteins, including amyloid proteins and apolipoproteins, that are differentially expressed in depressed mice compared to controls and aggressive mice. The findings suggest a psychopathogenic role of chronic social stress, potentially predisposing individuals to neurodegenerative and psychoemotional disorders. The research highlights the potential of using peripheral biomarkers to understand the comorbidity of depression with other diseases and to develop treatment strategies.

The study investigates the differential expression of proteins associated with bipolar disorder (BD) using the PeptideShaker software. The research highlights the challenges in diagnosing BD and the potential of proteomic studies to identify biomarkers for better diagnosis and treatment. The study identified ten proteins with significant differences in expression between BD patients and healthy individuals, with four proteins predominantly present in BD patients. The findings suggest that these proteins could play a role in the pathogenesis of BD and may serve as potential biomarkers for diagnosis and targets for therapy. The research emphasizes the importance of further studies to develop new diagnostic criteria and treatment options for BD.

Maria Zavialova, a Ukrainian journalist, shares her experiences as a refugee in Italy, highlighting the challenges and emotional turmoil faced by Ukrainian refugees. She discusses the guilt of leaving her country, the struggle to provide for her family, and the online ridicule faced by refugee women. Despite the hardships, she remains active in supporting Ukraine's war effort and urges the international community to continue supporting Ukraine against Russian aggression. Zavialova emphasizes the importance of maintaining hope and resilience amidst despair.

Maria Zavialova, a Ukrainian journalist, shares her harrowing experience as a refugee in Italy after fleeing the war in Ukraine. She details the emotional and physical challenges of exile, the guilt of leaving her country, and the struggle to support her family. Despite the hardships, she remains active in supporting the war effort and calls for continued international support for Ukraine. Zavialova emphasizes the importance of maintaining hope and resilience amidst the ongoing conflict.

A Ukrainian refugee shares her harrowing experiences of fleeing the war, dealing with guilt, and struggling to support her family in exile. She highlights the challenges faced by refugees, including financial difficulties and social stigma, while emphasizing the importance of international support for Ukraine. Despite the hardships, she remains resilient, contributing to the war effort through advocacy and support for Ukrainian soldiers. The narrative underscores the ongoing need for global attention and assistance to secure Ukraine's democracy and counter Russian aggression.