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William Chen

Taipei, Taiwan
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About William
Born and raised in Taipei City, William Chen holds BA in Radio and Television, minored in Ethnology, and MA in Religious Study from National Cheng-Chi University. At that time he became one of the first group of students using DV and NLE to make their own short films other than filming for school assignment. In 2007 his animated short “Cultural Reproduction Machine” was screened in Urban Nomad Film Festival. In 2010 he co-directed feature documentary “Dreams, a journey toward Wan Wan” with award-winning director Jim Wang with a theatrical release. After that he mainly working in media industry and international indie productions. In 2017, he wrote the narration for Discovery Channel for program “Secrets of Pangolin”. In 2018, his short film “Uncle Buddy” was screened in Urban Nomad Film Festival and a feature documentary “Metal Politics Taiwan”, which he worked as assistant director and editor has been broadcasted on ARTE in late 2018.
Currently he is involved in a couple of ongoing documentary projects and directing his own short play for stage.
Languages
English Chinese (Mandarin)
Services
Video Package (Web / Broadcast) Interview (Video / Broadcast) Documentaries
+3
Skills
Politics Current Affairs Technology
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Portfolio

Association of mental health diagnosis with race and all-cause mortality after a cancer diagnosis: Large-scale analysis of electronic health record data

28 Aug 2024  |  acsjournals.onlinelibrary.wiley.com
A large-scale analysis of electronic health record data from 54,852 cancer patients reveals significant racial disparities in the diagnosis and treatment of mental health conditions following a cancer diagnosis. Minority patients were less likely to receive a mental health diagnosis, prescription medication, or mental health-related visits compared to non-Hispanic White patients. The study found that new mental health diagnoses and prescription medications within 12 months of a cancer diagnosis were associated with elevated all-cause mortality in the short term. These findings highlight missed opportunities for addressing cancer-related distress among minority patients and support guidelines for equitable mental health screening and treatment in cancer care.

Non-fungible tokens (NFT) was very trendy around 2021 and 2022. As a writer/director, I would like to document how artists try to seize the opportunity to create and experiment with this new application for the potential future reference. Luckily Discovery Channel Taiwan and TaiwanPlus together picked this pitch up and allowed me to make it happen.

Portfolio Analysis at Scale: Running Risk and Analytics on 15+ Million Portfolios Every Day

28 Mar 2024  |  InfoQ
BlackRock's Aladdin Wealth product performs portfolio analysis on over 15 million portfolios daily, leveraging sophisticated analytics and risk management techniques. The system processes millions of API calls and handles significant surges in demand. Key insights for achieving this scale include optimizing computational graphs, storing data in multiple formats, evaluating new technology on a total cost basis, using and contributing to open source, considering modularization dimensions, and being cautious about external dependencies. The text underscores the importance of efficient code, data consistency, and strategic use of technology to maintain high performance and reliability.

Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance

12 Jan 2024  |  Nature
The study investigates the genetic, epigenetic, and molecular mechanisms underlying Schwann cell tumor de-differentiation and treatment resistance. Through multiplatform bulk and single-cell molecular profiling, the research identifies distinct DNA methylation groups among Schwann cell tumors, revealing that Group 1 tumors are malignant and de-differentiated, Group 2 tumors are in a transitory state, and Group 3 tumors are benign and differentiated. The study highlights the role of PRC2 loss in Schwann cell tumor de-differentiation and MEK inhibitor resistance, suggesting that targeting PAK1 in combination with MEK inhibitors could overcome treatment resistance. The research integrates data from human patients and preclinical models to propose potential therapeutic strategies for NF1-mutant Schwann cell tumors.

The Top 10 Classic Board Games for Family Fun

03 Dec 2023  |  williamthewriter.medium.com
Classic board games like Monopoly, Scrabble, Chess, Clue, Risk, Trivial Pursuit, Connect Four, Battleship, Pictionary, and Candyland offer timeless entertainment and foster family bonding. These games encourage strategic thinking, creativity, and friendly competition. Toysocity is recommended for purchasing these games.

The Art of Lego Building: Unlocking Imagination and Creativity

27 Nov 2023  |  williamthewriter.medium.com
Lego building is celebrated as a tool for unlocking imagination and fostering creativity in both children and adults. The article highlights how Lego promotes problem-solving skills, spatial awareness, and creative thinking. It also discusses the vibrant Lego community and offers tips for getting started with Lego building. The piece emphasizes that Lego is not just a toy but a means of self-expression and creativity, with themed sets catering to various interests.

With A Sincere Heart

01 Oct 2023  |  Prestige Online - HongKong
Jam Hsiao returns with a new album 'Wild,' embracing a pure and sincere state as a singer. The album, produced in Norway, reflects his personal growth and recent life changes, including his marriage to long-time manager Summer Lin. Hsiao emphasizes the importance of breaking free from norms to discover new surprises and the significance of effort and personal satisfaction in his artistic journey. The article highlights his passion for music and acting, his reflections on love and marriage, and his belief in living in the moment while planning for the future.

DIY Craft Projects for Kids: Unleashing Creativity

01 Oct 2023  |  williamthewriter.medium.com
DIY craft projects for kids are highlighted as a means to engage children, enhance their motor skills, cognitive development, and self-expression. The article details five specific projects: Nature Collage, Popsicle Stick Puppets, Yarn Bracelets, Paper Mache Crafts, and Flower Press, all of which are simple, affordable, and can be done with materials readily available at home. These activities encourage creativity, reduce screen time, and provide opportunities for storytelling and personal expression.

Reliability of patient self-report of cognition, awareness, and consciousness during seizures

01 Oct 2023  |  Wiley Online Library
The study investigates the reliability of patient self-reports on cognitive and behavioral functions during seizures by comparing subjective questionnaire responses with objective behavioral ratings from video-EEG monitoring. The findings indicate that patient self-reports of memory and awareness during seizures show good concordance with objective measures, while reports on responsiveness, speech, and consciousness are less reliable. The study suggests that patient reports on memory impairment during seizures are the most reliable, and other functional impairments should be determined based on objective observations.

The Psychology Behind Collecting Trading Cards

01 Oct 2023  |  williamthewriter.medium.com
Collecting trading cards captivates enthusiasts through nostalgia, the thrill of the hunt, community building, exclusivity, and the pleasure of organization. The hobby offers psychological benefits such as escapism, relaxation, and a sense of purpose. However, excessive collecting can lead to hoarding behaviors linked to underlying psychological issues. Embracing the joy of collecting with mindfulness can make it a rewarding and fulfilling activity.

Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses

01 Oct 2023  |  Nature
The study investigates the use of targeted gene expression profiling to predict outcomes and responses to radiotherapy in meningioma patients. Using data from the UCSF discovery cohort and other clinical validation cohorts, the research demonstrates that a 34-gene expression risk score can effectively stratify meningiomas by risk levels. The gene expression biomarker shows high concordance across different platforms and conditions, and remains prognostic across various clinical and molecular classification systems. The findings suggest that the gene expression biomarker could help identify meningiomas where postoperative radiotherapy might be safely omitted, even in high-risk clinical settings.

Commentary: If you love eating vegetables, why not homegrown greens?

01 Oct 2023  |  CNA
Singapore's local farming industry faces challenges in encouraging consumers to embrace homegrown vegetables due to higher prices compared to imported alternatives. Despite the government's goal to produce 30% of nutritional needs locally by 2030, consumer buy-in remains low, leading to unsold produce. Urban farming practices, such as rooftop and indoor farming, offer potential solutions but come with higher operational costs. Community-supported agriculture (CSA) could foster direct relationships between farmers and consumers, enhancing demand and sustainability. Embracing local produce is crucial for a resilient food ecosystem in Singapore.

The Joy of Building LEGO Sets: From Bricks to Masterpieces

01 Oct 2023  |  williamthewriter.medium.com
Building LEGO sets is a beloved pastime that offers an immersive experience, fostering creativity, problem-solving skills, and strategic thinking. The article explores the unique appeal of LEGO sets, their diverse themes, and the multitude of benefits they offer, including enhancing fine motor skills, patience, and social skills. It also discusses the evolution of LEGO sets with the incorporation of new technologies and licensed themes. Building LEGO sets is portrayed as a rewarding hobby for individuals of all ages, providing a timeless joy that transcends generations.

The Therapeutic Benefits of Coloring Books for Adults

01 Oct 2023  |  williamthewriter.medium.com
Coloring books for adults have gained popularity as a form of relaxation and self-expression, offering therapeutic benefits such as stress reduction, improved focus, and mindfulness. The activity promotes mental well-being by allowing individuals to engage in creative expression without the pressure of starting from scratch. Coloring can also serve as a social activity, fostering connection and bonding. Choosing the right coloring book that resonates with personal preferences enhances the experience, making it a valuable tool for relaxation and mental health.

Molecular Features of Resected Melanoma Brain Metastases, Clinical Outcomes, and Responses to Immunotherapy

17 Aug 2023  |  jamanetwork.com
This study investigates the molecular features of resected melanoma brain metastases and their clinical outcomes, focusing on the BRAF V600E variant. The research reveals that BRAF V600E variant lesions are associated with worse intracranial progression-free survival and overall survival compared to BRAF wildtype lesions. Single-cell sequencing indicates that BRAF V600E variant brain metastases have fewer immune cell types. Immunotherapy shows improved outcomes for patients with BRAF wildtype but not for those with BRAF V600E variant brain metastases. The study suggests that BRAF status is a crucial molecular biomarker for guiding systemic therapy selection in melanoma brain metastases.

Biological ion exchange shows promise to deliver safe water

01 Jun 2023  |  Environmental Science & Engineering Magazine
The small island community of Gillies Bay faced significant challenges with its water system, particularly in removing natural organic matter (NOM) due to a lack of funding. A pilot study explored the use of biological ion exchange as a cost-effective solution, showing promise for delivering safe water to small and hard-to-access communities.

Verifying Low-Temperature Soldering Compliance For CO2 Savings And Enhanced Product Performance

01 Jun 2023  |  Semiconductor Engineering
Low-temperature soldering (LTS) offers significant environmental benefits by reducing CO2 emissions and energy consumption in electronic manufacturing. Intel and Lenovo introduced LTS, allowing reflowing at 190°C, significantly lower than conventional methods. Winbond has committed to LTS, enhancing product reliability and reducing environmental impact. The company has achieved compliance with JEDEC standards, ensuring high yield and quality. LTS also simplifies production processes and supports faster technology scaling. By 2027, over 20% of electronics manufacturers are expected to adopt LTS, contributing to a more sustainable future.

Renewable Energy is a Privilege

26 Jan 2023  |  medium.com
The article discusses the challenges and inequities associated with the transition to renewable energy, highlighting that the initial investment and social costs often exclude marginalized communities, both in developed and developing countries. It argues that while renewable energy is crucial for addressing climate change, the transition process can exacerbate existing inequalities, particularly affecting poorer communities who bear the brunt of energy transitions and environmental regulations. The article calls for policies that consider equity and support vulnerable communities to ensure successful renewable energy transitions.

In 2017/2018, I worked as the main writer of the English/International version of Secrets of Pangolin for Discovery Channel Taiwan. The series later was nominated for Golden Bell Awards, the most prestigious TV awards in Taiwan

Singapore loves eggs but can we make production friendlier for hens?

30 Sep 2021  |  CNA
Singapore's high egg consumption has led to significant reliance on imports, with local production covering only 28% of demand. The introduction of a new egg farm by Japanese producer ISE Food Holdings aims to enhance food security but faces opposition from PETA due to animal welfare concerns. The shift from free-range to caged systems has been driven by disease control and efficiency, though it raises animal welfare issues. Technological advancements and sustainable practices, including plant-based egg alternatives by local startups, are being explored to make egg production more humane and environmentally friendly. The NTU Food Science and Technology Programme is working on innovative solutions to reduce the environmental impact and improve the resilience of local egg production.

Leveraging Multi-Protocol PHY for PCIe to Cope with SoC Design Complexity

18 May 2021  |  www.chipestimate.com
The article discusses the increasing complexity of SoC design in the post-Moore's Law era, emphasizing the role of PCIe as a primary I/O interconnect. It highlights the benefits of using a multi-protocol PHY IP block, particularly Cadence's 10Gbps Multi-Protocol Multi-Link PHY IP, which supports various protocols like PCIe, USB, SATA, DisplayPort, and Ethernet. The multi-protocol PHY simplifies design verification, reduces development costs, and shortens time to market by allowing flexible protocol configurations within a single PHY instance. The article underscores the advantages of Cadence's technology in addressing market demands for higher performance and flexible SoC designs.

Efficacy and Safety of Stereotactic Radiosurgery for Brainstem Metastases

13 May 2021  |  jamanetwork.com
The systematic review and meta-analysis evaluated the efficacy and safety of stereotactic radiosurgery (SRS) for brainstem metastases (BSM) across 32 studies involving 1446 patients. The findings indicate high local control rates (86%) and symptom relief (50%-60%) with rare significant toxic effects (2.4%) and low death rates from BSM progression (2.7%). The study suggests that SRS is effective and safe for BSM, comparable to its use for nonbrainstem brain metastases, and recommends considering SRS for BSM patients in future clinical trials of targeted or immunotherapy for brain metastases.

Radiation Therapy Continuation for a Patient Diagnosed with COVID-19 in a High-volume Radiation Oncology Practice

06 Apr 2020  |  www.appliedradiationoncology.com
A case report from a New York academic radiation oncology practice details the continuation of radiation therapy for a morbidly obese woman diagnosed with COVID-19. The patient, undergoing treatment for adrenal cortical adenocarcinoma, tested positive for SARS-CoV-2 after exposure to an infected coworker. The practice implemented strict protocols, including PPE for staff and scheduling adjustments, to ensure the safety of both the patient and healthcare workers. The patient completed her radiation therapy successfully, highlighting the practice's commitment to balancing cancer treatment with infection control during the pandemic.

Matias Wireless Aluminum Tenkeyless Keyboard Review

07 Mar 2020  |  BWOne
The Matias Wireless Aluminum Tenkeyless Keyboard is designed primarily for Apple users, offering compatibility with various devices including smartphones, tablets, and PCs. It features a slim, portable design with an aluminum top and hard plastic back, weighing under 2 lbs. The keyboard supports multiple device pairing via Bluetooth and includes chiclet keys similar to a Mac layout. It replaces F13-F15 keys with Bluetooth buttons for easy device pairing. The keyboard charges via micro USB, with a full charge taking approximately 5 hours. While it lacks backlit keys, it is compact and travel-friendly, priced at USD 89.99.

Angiotensin II receptor blocker losartan exacerbates muscle damage and exhibits weak blood pressure-lowering activity in a dysferlin-null model of Limb-Girdle muscular dystrophy type 2B

12 Aug 2019  |  journals.plos.org
Losartan, an angiotensin II receptor blocker, exacerbates muscle damage and shows weak blood pressure-lowering activity in a dysferlin-null mouse model of Limb-Girdle muscular dystrophy type 2B (LGMD2B). The study reveals that losartan increases muscle fibrosis and fat infiltration, and elevates plasma triglycerides and cholesterol levels in dysferlin-null mice. The findings suggest that LGMD2B patients may be resistant to losartan's primary blood pressure-lowering effects and may experience accelerated muscle wasting and dyslipidemia. The study urges caution in using angiotensin II receptor blockers in this patient population.

We Can Make Large Dams More Friendly to the Environment

19 Apr 2018  |  Scientific American
Large dams provide essential services like hydropower and water security but significantly disrupt freshwater ecosystems, affecting native species and promoting invasive ones. Research from the University of Washington suggests optimizing dam operations to balance agricultural water needs, benefit native fish, and deter invasive species. By adjusting water release timings, it is possible to support both human and ecological needs, even in the face of climate change. While these solutions won't eliminate all environmental impacts of dams, they represent a significant step towards more sustainable water management.

ADHD and Insomnia: How to Help Your Child Sleep Better

14 Dec 2004  |  Child Psychology Resources by Dr. Tali Shenfield
ADHD and insomnia are closely linked, with many children experiencing sleep difficulties due to ADHD symptoms and medications like Adderall. The bidirectional relationship between ADHD and sleep issues exacerbates both conditions, making it crucial for parents to prioritize healthy sleep habits. Proper diagnosis and treatment, including lifestyle changes, medication adjustments, and therapy, can help manage both ADHD and insomnia. Strategies such as maintaining consistent routines, limiting screen time, and encouraging outdoor exercise can improve sleep quality and overall well-being for children with ADHD.

How To Raise Compassionate Children In A Dangerous World

14 Dec 2004  |  Child Psychology Resources by Dr. Tali Shenfield
The article discusses strategies for raising compassionate children in a world filled with violence and aggression. It emphasizes the importance of early education in empathy, the role of parental modeling, and the benefits of surrounding children with multiple kind role models. The article also provides four specific strategies: encouraging compassionate reading, guiding television choices, finding volunteer opportunities, and providing a secure home environment.

Is Dysgraphia a Learning Disability? The Handwriting Disorder Explained

14 Dec 2004  |  Child Psychology Resources by Dr. Tali Shenfield
Dysgraphia is a learning disability affecting handwriting and fine motor skills, often present from birth and persisting into adulthood. It is characterized by difficulties in writing legibly, spelling, and organizing thoughts on paper, despite normal reading and verbal abilities. The condition is often under-diagnosed, with symptoms sometimes mistaken for sloppiness or laziness. Dysgraphia can co-occur with other conditions like ADHD and autism, complicating diagnosis. Early intervention, occupational therapy, and assistive technology can help manage symptoms and improve writing skills. Dysgraphia is distinct from dyslexia and dyscalculia, though symptoms may overlap. Career paths in arts, sales, and technology are suitable for individuals with dysgraphia, leveraging their strengths in creativity and verbal communication.
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